Impact of Cardiovascular Risk Factors on Cognitive Scores Over Time

 
   Lead Investigator:    Katherine Irimata
   Institution      :    Arizona State University
   E-Mail           :    katherine.irimata@gmail.com
   Proposal ID      :    789


   Publications:


1  Irimata K
   Impact of the presence of select cardiovascular risk factors on cognitive change
   2017   Abstract  American Public Health Association 2017 Annual Meeting Expo , 

   ACCEPTED



2  Irimata KE, Dugger BN, Wilson JR
   Impact of the presence of select cardiovascular risk factors on cognitive changes among dementia subtypes
   Journal Article  Curr Alzheimer Res,15:1032-1044,2018,PMC6162109

   PUBLISHED





   Proposal Description:
   With a growing elderly population, many studies have been performed to            understand conditions associated with Alzheimer???s Disease (AD). One specific    area of interest is investigating the association of cardiovascular risk          factors, which are potentially modifiable, and AD. We aim to evaluate the         impact of cardiovascular risk factors directly on a measure of cognition. The     cognition measure will be derived from a neuropsychological test, such as the     Mini-Mental State Examination (MMSE) or the Montreal Cognitive Assessment         (MoCA). This study will investigate commonly identified cardiovascular risk       factors, such as blood pressure, cholesterol, BMI, as well as demographic         information and family history.                                                   Previous longitudinal studies have revealed inconclusive or conflicting results   on the relationship of specific cardiovascular risk factors and AD. In            addition, the studies performed investigate varying populations that may be       limited to a specific gender or age group, or may be grouped by similar health    outcomes (i.e. diabetic). Our goal is to better understand how cardiovascular     risk factors are related to cognition over time, for a broader population. We     expect that many of the common cardiovascular risk factors will be highly         associated with a decline in cognition, and we aim to provide insight to this     research area for a wide range of demographics.